By CASC4DE October 24, 2024
🔬 A new study from Hailey E. Hampson et al. published in Science of the Total Environment reveals that exposure to per- and polyfluoroalkyl substances (PFAS) may impair kidney function, with the gut microbiome and metabolites playing a crucial role. The study found that higher PFAS levels were associated with lower kidney function and changes in gut bacteria, particularly those with anti-inflammatory properties. These findings could lead to future interventions targeting the microbiome.
⚠️ Studies have found associations between PFAS exposure and impaired estimated glomerular filtration rates (eGFR) in adults (Lin et al., 2021; Blake et al., 2018). However, research on the effects of PFAS exposure in young adulthood, a critical development window for kidney function (Hussain et al., 2023), and the potential mechanism involved is limited. Although previous work has demonstrated a strong link between the gut microbiome, altered metabolic profiles and risk of CKD, no studies have examined how exogenous environmental chemicals may impact these associations.
🔹CASC4DE provides a more comprehensive view of the presence and distribution of PFAS in the environment through fluorine NMR 🧲. We offer solutions for accurate PFAS detection and quantification in various matrices, aiding industries and public research efforts to address these health and environmental risks.
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